Search on: ALKALOIDS, VERATRUM 
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Descriptor English:   Veratrum Alkaloids 
Descriptor Spanish:   Alcaloides de Veratrum 
Descriptor Portuguese:   Alcaloides de Veratrum 
Synonyms English:   Alkaloids, Veratrum  
Tree Number:   D03.132.920
Definition English:   Alkaloids with powerful hypotensive effects isolated from American or European Hellebore (Veratrum viride Ait. Liliaceae and Veratrum album L. Liliaceae). They increase cholinergic and decrease adrenergic tone with appropriate side effects and at higher doses depress respiration and produce cardiac arrhythmias; only the ester alkaloids have been used as hypotensive agents in specific instances. They have been generally replaced by drugs with fewer adverse effects. 
Indexing Annotation English:   antihypertensives
Pharmacological Action:   Antihypertensive Agents
 
History Note English:   75 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   15109 
Unique Identifier:   D014704 

Occurrence in VHL:
 

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